37 terms in this chapter
absolute neutrophil count
group of disorders generally defined as a reduction in the mass of circulating red blood cells or hemoglobin
group of disorders where the immune system misidentifies RBCs as foreign and creates autoantibodies that attack and destroy them
procedure to obtain a small sample of bone marrow tissue for diagnostic evaluation of blood disorders and cancers
treatment that replaces damaged or destroyed bone marrow with healthy stem cells; also called hematopoietic stem cell transplant
complete blood count
serious, life-threatening condition with widespread, unrestricted microvascular blood clotting followed by severe hemorrhage
blood test that measures the speed at which RBCs settle to the bottom of a tube; used to detect inflammation
hematocrit
blood
inherited bleeding disorder where blood doesn't clot properly due to deficiency of clotting factors (usually factor VIII or IX)
the physiological process that stops bleeding at the site of an injury
hemoglobin
disorder with severe platelet deficiency resulting in abnormal blood clotting, marked by tiny purple bruises (purpura) under the skin
cancer of the body's blood-forming tissues, including the bone marrow, causing excessive production of abnormal white blood cells
mean corpuscular hemoglobin
mean corpuscular hemoglobin concentration
mean corpuscular volume
cancer of plasma cells in the bone marrow, leading to bone lesions, anemia, and renal impairment
clonal bone marrow disorder with ineffective hematopoiesis; formerly called myelodysplastic syndrome
chronic form of megaloblastic anemia caused by a deficit in intrinsic factor, which prevents vitamin B12 absorption
eat, swallow
the clear, yellowish, liquid part of the blood that carries cells and proteins throughout the body
platelets
chronic disorder marked by an abnormal increase in number and mass of all bone marrow cells, especially RBCs, resulting in increased blood viscosity
partial thromboplastin time
red blood cell (erythrocyte)
red cell distribution width
blood plasma from which the clotting factors (fibrinogen) have been removed
hereditary hemoglobinopathy causing red blood cells to become crescent-shaped, leading to hemolysis, pain crises, and organ damage
treatment that infuses healthy stem cells into a patient to restore bone marrow function; often used for leukemia and lymphoma
inherited blood disorder with reduced hemoglobin production, causing microcytic anemia; types include alpha and beta thalassemia
clot, thrombus
condition of abnormally low platelet count, increasing risk of bleeding
potentially fatal reaction of antibodies in transfused blood to RBCs in the recipient's blood, or vice versa
inherited bleeding disorder caused by deficiency or dysfunction of von Willebrand factor, leading to impaired platelet adhesion
white blood cell (leukocyte)