57 terms in this chapter
antibody
late-stage infection with HIV which progressively weakens the immune system
gland
adenoid
antigen
acquired immunodeficiency syndrome
life-threatening systemic allergic reaction to a substance to which the body was previously sensitized
inflammatory response causing degenerative changes in spinal vertebrae, sacroiliac joints, and connective tissues
bacteria
immunotherapy agent that binds to both a tumor antigen and a T-cell receptor, redirecting T-cells to kill cancer cells
cancer or carcinoma
genetically engineered T-cells expressing chimeric antigen receptors to target and kill cancer cells
complex chronic disorder marked by severe fatigue unrelieved by rest, worsened by mental or physical activity
group of disorders with persistent or recurrent Candida fungal infections on skin, nails, or mucous membranes
primary immunodeficiency disorder with low immunoglobulin levels and increased susceptibility to infections
common variable immunodeficiency
autoimmune inflammatory myopathy with characteristic skin rash, affecting muscles and skin
Epstein-Barr virus
enzyme immunosorbent assay
acute infection causing sore throat, fever, fatigue, and enlarged lymph nodes; also called mononucleosis
erythrocyte sedimentation rate
complication of bone-marrow transplantation where lymphoid cells from donated tissue attack the recipient
graft-versus-host disease
human immunodeficiency virus
type of lymphatic cancer; also called Hodgkin lymphoma
immunoglobulin
most common primary immunodeficiency, characterized by low levels of IgA, often asymptomatic or with recurrent infections
immune, protection, safe
drug class that blocks immune checkpoints (e.g., PD-1, CTLA-4) to enhance T-cell antitumor activity
treatment that uses the body's immune system to fight diseases, including cancer, autoimmune disorders, and infections
Kaposi's sarcoma
lymph
lymph gland (node)
lymphatic vessel
lymph cell
cancer of lymphatic tissue not related to Hodgkin's disease
metastasis, metastasize
overlap syndrome with features of SLE, scleroderma, and polymyositis, with high titers of anti-U1-RNP antibodies
lab-engineered antibodies that bind to specific antigens; used in cancer, autoimmune, and infectious diseases
group of more than 30 types of malignancies of B and T lymphocytes
Pneumocystis carinii pneumonia, Pneumocystis pneumonia
process in which specialized white blood cells (phagocytes) engulf and destroy microorganisms, foreign antigens, and cell debris
type of pneumonia associated with AIDS
disorder causing slow onset of muscle weakness and pain in trunk, progressing to neck, shoulders, back, hip
severe combined immunodeficiency
group of chronic autoimmune diseases causing inflammatory and fibrotic changes to skin, muscles, joints, tendons, cartilage
serum
rare, life-threatening primary immunodeficiency with absent T-cell and B-cell function; also called 'bubble boy disease'
autoimmune disorder causing dysfunction of salivary glands and lacrimal glands; also known as Sicca syndrome (formerly Sjögren's syndrome)
systemic lupus erythematosus